MOTS-c (Mitochondrial-Derived Peptide)
Precision Synthesized | Research Grade Compound
Next-generation mitochondrial signaling peptide at the forefront of metabolic and performance research.
Precision synthesized. Research-grade quality.
OVERVIEW
MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome, distinguishing it from traditional peptides produced by nuclear DNA. As a signaling molecule, it is studied for its role in communication between the mitochondria and the nucleus, influencing how cells adapt to metabolic stress and energy demands.
Research has focused on its ability to regulate pathways associated with energy production, glucose utilization, and cellular efficiency. Under metabolic stress conditions, MOTS-c has been observed to translocate to the nucleus, where it may influence gene expression linked to metabolic balance and adaptive cellular responses.
RESEARCH FOCUS AREAS
Mitochondrial Signaling & Energy Regulation
Investigated for its role in mitochondrial communication and cellular energy production pathways.
Metabolic Regulation & Fat Oxidation
Studied in relation to mechanisms associated with fat metabolism, energy utilization, and weight management pathways.
Glucose Uptake & Insulin Sensitivity
Observed in research exploring glucose handling, insulin signaling pathways, and metabolic efficiency.
Exercise-Mimetic Pathways
Preliminary studies indicate involvement in pathways associated with physical performance, endurance signaling, and skeletal muscle efficiency.
RESEARCH APPLICATIONS
- Metabolic regulation and energy balance studies
- Fat oxidation and weight management pathway research
- Mitochondrial function and signaling analysis
- Glucose metabolism and insulin response studies
- Performance and endurance-related pathway modelling
SCIENTIFIC REFERENCES
MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9570330/
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis:
https://pubmed.ncbi.nlm.nih.gov/25738892/
MOTS-c restores mitochondrial respiration in type 2 diabetic heart:
https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2025.1602271/full
MOTS-c reduces myostatin and muscle atrophy signaling:
https://journals.physiology.org/doi/abs/10.1152/ajpendo.00275.2020
IMPORTANT NOTICE
This compound is supplied strictly for laboratory research purposes only.
Demure Peptides™ operates as a private sourcing and payment facilitation platform, connecting clients to independent third-party supply channels. All fulfilment, handling, and packaging are conducted externally.
This product is not intended for human consumption.
This product has not been evaluated by the South African Health Products Regulatory Authority and is not intended to diagnose, treat, cure, or prevent any disease.
Product visuals displayed on this platform are representative of the Demure Peptides™ brand experience. Actual supplied items are fulfilled through independent third-party laboratories and may vary in size, packaging, and branding.
ADDITIONAL INFORMATION
- Peptide Name: MOTS-c
- Category: Metabolic / Mitochondrial Research Peptide
- Format: Vial
- CAS Number: 1627580-64-6
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